Specialists

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Osteosarcoma

Basics Description The most common primary malignant bone tumor in children and young adolescents May occur occasionally in older adults but is much less common than chondrosarcoma and MFH May occur within other lesions (secondary sarcoma) such as Paget disease, bone infarcts, and irradiated bone A highly malignant tumor with invasive local growth and […]

Giant Cell Tumor

Basics Description A benign but often locally aggressive neoplasm, characterized by large numbers of uniformly distributed, osteoclastlike giant cells and a background population of plump, epithelioid-to-spindle mononuclear cells. The vast majority of these tumors are located near the articular end of a tubular bone; ~50% occur in the knee. Other frequently involved sites: Distal […]

Aneurysmal Bone Cyst

Basics Description Destructive, painful, lytic bone lesions occurring in young patients May occur primarily in bone (de novo) or develop within another benign bone lesion Can be locally aggressive and can cause a bone to balloon as a result of aneurysmal cystic expansion Occurs most often at the proximal ends of long bones and […]