Specialists

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Autologous Tissues

The use of autologous tissues about the knee has been commonplace for several years, and has included the transplantation of local tissue, transfer of remote tissue, and finally the genetic production of cloned tissue from knee cartilage cells .

A technique that has been used in the knee is transfer of autologous tissue from other […]

Platelet-Rich Plasma Therapy

What is PRP?

PRP refers to a concentrate of platelets in plasma that is higher than that of normal circulating platelets in the body. Beyond this concept, however, there is considerable variation in its definition.

Platelets have a vital role in the healing of injured tissues. The alpha granules of platelets contain growth factors which […]

Summary

Understanding the structure of the meniscus and its process of repair has been critical in advancing surgical techniques and increasing healing rates following meniscal repair. Knowledge of the circumferential orientation of the collagen fibers has lead to the preferred position of sutures—vertical mattress.

Increasing knowledge of normal meniscal healing and meniscal vascularity has lead to […]

Cellular Response to Injury

The ability of fibrochondrocytes within a meniscus to mount a reparative response is dependent in part upon cellular activity. Cytokines and growth factors present during the inflammatory response to injury may promote meniscal healing through enhancement of cell migration, cell division, and the production of extracellular matrix.

While no specific growth factor has been shown […]

Basic Science of Meniscal Repair

Thomas Annandale was credited with the first surgical repair of a torn meniscus in 1883 . It was not until 1936, when King published his classic experiment on meniscus healing in dogs, that the actual biological limitations of meniscus healing were set forth. King demonstrated that for meniscal lesions to heal, they must communicate with […]

Growth Factors

A vast and rapidly growing literature abounds on a class of peptides commonly called growth factors. Accelerated healing of skin wounds has been reported after local application of several growth factors.

After injury, the platelets travel to the wound site, form a clot, and hemostasis is obtained. Platelets secrete peptides such as platelet-derived growth factor […]

Platelet Rich Plasma Injection Grafts for Musculoskeletal Injuries: A Review

Abstract

In Europe and the United States, there is an increasing prevalence of the use of autologous blood products to facilitate healing in a variety of applications. Recently, we have learned more about specific growth factors, which play a crucial role in the healing process. With that knowledge there is abundant enthusiasm in the application […]

Prolotherapy Therapy with Platelet Rich Plasma

Tendons and ligaments connect muscles to bones, making it possible to do all kinds of physical activities. Overuse or damage to tendons over a long period of time causes the collagen fibers that make up the tendons to form small tears, a condition called Tendinosis. Ligaments are composed of collagen fibers and hold bones together, […]

A Patient’s Guide to Anterior Lumbar Fusion with Cages

Introduction

Anterior lumbar fusion is an operation done on the front (the anterior region) of the lower spine. Fusion surgery helps two or more bones grow together into one solid bone. Fusion cages are new devices, essentially hollow screws filled with bone graft, that help the bones of the spine heal together firmly. Surgeons use […]